Understanding and treating atrial fibrillation through genetic insights
Atrial Fibrillation Post-GWAS: Mechanisms to Treatment
This study is looking at the genes that might cause atrial fibrillation, a common heart rhythm issue, to find better ways to treat it, so that patients can have more effective and personalized care.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10896373 on NIH RePORTER |
What this research studies
This research investigates the genetic mechanisms behind atrial fibrillation (AF), a common heart rhythm disorder, to develop better treatment options. By analyzing genetic data and how it interacts with environmental factors and other health conditions, the team aims to identify new therapeutic targets. The research utilizes a unique biorepository of human atrial tissue and genomic data to translate these findings into personalized treatment strategies for patients with AF. The goal is to improve the efficacy of current therapies and potentially discover new pharmacological agents.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with atrial fibrillation, particularly those who may not respond well to current treatments.
Not a fit: Patients without a diagnosis of atrial fibrillation or those with other unrelated cardiac conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for patients with atrial fibrillation.
How similar studies have performed: Previous research has shown promise in using genetic insights to inform treatment strategies for various conditions, suggesting potential for success in this area as well.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Chung, Mina Kay — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Chung, Mina Kay
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.