Understanding and targeting the immune environment in lymphoma
Epigenetic basis and therapeutic targeting of the unique lymphoma immunological niche
['FUNDING_P01'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-10847986
This study is looking at how certain genetic changes in diffuse large B-cell lymphoma (DLBCL) affect the cancer's relationship with the immune system, with the goal of finding better treatments for patients like you.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10847986 on ClinicalTrials.gov |
What this research studies
This research investigates diffuse large B-cell lymphoma (DLBCL), a type of aggressive cancer that arises from B-cells. It focuses on the genetic mutations that affect how these cancer cells interact with their surrounding immune environment. By examining the mechanisms behind these mutations and their impact on the lymphoma microenvironment, the research aims to develop targeted therapies that can improve treatment outcomes. The team utilizes advanced technologies and models to explore these complex interactions and their implications for patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with diffuse large B-cell lymphoma, particularly those with varying responses to current therapies.
Not a fit: Patients with other types of lymphoma or those who do not have B-cell malignancies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for patients with diffuse large B-cell lymphoma.
How similar studies have performed: Previous research has shown promise in targeting the immune environment in various cancers, suggesting that this approach could yield significant advancements in lymphoma treatment.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CERCHIETTI, LEANDRO C — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: CERCHIETTI, LEANDRO C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.