Understanding and targeting how cancer cells divide
Core A: Determining and targeting mechanisms controlling cancer cell division
This study is looking at how certain genes and proteins help control the way cancer cells grow and divide, with the hope that understanding these processes better will lead to new treatments for patients with cancer.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11046675 on NIH RePORTER |
What this research studies
This research investigates the mechanisms that control cancer cell division, focusing on the roles of specific genes and proteins involved in the cell cycle. By examining mutations in oncogenes and tumor suppressor genes, the project aims to uncover how these changes contribute to cancer progression. The research employs an interdisciplinary approach, combining insights from various scientific fields to explore the Rb pathway, which is crucial for regulating cell growth and differentiation. Patients may benefit from advancements in targeted therapies that arise from a deeper understanding of these cellular processes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cancers related to mutations in the Rb pathway or those with a family history of such cancers.
Not a fit: Patients with cancers unrelated to the Rb pathway or those who do not have genetic predispositions to these mutations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new targeted therapies that improve cancer treatment outcomes.
How similar studies have performed: Previous research has shown promising results in targeting similar pathways in cancer treatment, indicating a potential for success in this approach.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Sage, Julien — Stanford University
- Study coordinator: Sage, Julien
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.