Understanding and targeting factors that lead to stomach cancer
Molecular Understanding and Targeting of Determinant Factors in Gastric Tumorigenesis
This study is looking at how gastric cancer develops to find new ways to treat and prevent it, using special mice and human samples to learn more about the proteins that help cancer grow, so we can create better therapies for people affected by this disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11052587 on NIH RePORTER |
What this research studies
This research focuses on gastric cancer, a serious and common type of cancer, by investigating the molecular mechanisms that contribute to its development. The team aims to identify specific molecular targets that can be used to create new treatments and preventive strategies for gastric cancer. By studying genetically modified mice and human tissue samples, they hope to uncover how certain proteins influence cancer stem cells and tumor growth. This approach could lead to innovative therapies that specifically target the underlying causes of gastric cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults diagnosed with gastric cancer or those at high risk due to chronic Helicobacter pylori infection.
Not a fit: Patients with early-stage gastric cancer or those without any risk factors for gastric cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve survival rates and quality of life for patients with gastric cancer.
How similar studies have performed: Previous research has shown promising results in targeting molecular pathways in other cancers, suggesting that this approach could also be effective for gastric cancer.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Zuo, Xiangsheng — University of Tx Md Anderson Can Ctr
- Study coordinator: Zuo, Xiangsheng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.