Understanding and reversing factors that lead to early-onset colorectal cancer
PROSPECT-Global Consortium and Risk Factor Discovery
This study is looking into why more people under 50 are getting colorectal cancer, and it aims to find ways to prevent it by understanding the biological and environmental factors involved.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11047262 on NIH RePORTER |
What this research studies
This research investigates the complex factors that contribute to the rising rates of colorectal cancer in individuals under 50 years old. By collaborating with experts across various fields, the project aims to identify biological and environmental influences that disrupt normal bodily functions and lead to cancer. The team will utilize advanced animal models and study specific precursors, such as adenomatous polyps, to develop effective prevention strategies. The goal is to translate these findings into actionable steps that can help reduce the incidence of early-onset colorectal cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals under 50 years old who are at risk for colorectal cancer or have a family history of the disease.
Not a fit: Patients over the age of 50 or those without risk factors for colorectal cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies for colorectal cancer in younger individuals.
How similar studies have performed: Previous research has shown promise in understanding risk factors for colorectal cancer, but this approach is innovative in its focus on early-onset cases.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Cao, Yin — Washington University
- Study coordinator: Cao, Yin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.