NIH-funded research P01 program project

Understanding and reversing age-related hearing loss

Official title: Determinants of age-induced hearing loss and reversal strategies

Funded at University of Arizona · NIH-10910232 · Data updated 2026-11-12

This study is looking into why many older adults experience hearing loss as they age, hoping to find ways to help improve or prevent it, so people can stay connected and feel better.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionUniversity of Arizona
NIH-funded
Lab location1 site (Tucson, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$2,413,607
NIH project number7P01AG051443-07
Project IDNIH-10910232 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults experiencing hearing loss or related auditory issues.

Less likely to help

Patients with hearing loss due to non-age-related factors, such as noise exposure or genetic conditions, may not benefit from this research.

What this research studies

This research investigates the causes of age-related hearing loss, known as presbycusis, which affects many older adults and can lead to social isolation and depression. The team hypothesizes that changes in auditory neurons due to aging lead to loss of specific neuron types and changes in how the brain processes sound. By analyzing these changes across different parts of the auditory system, the researchers aim to identify potential strategies to reverse or mitigate hearing loss. The study involves collaboration among experts in genetics, physiology, imaging, and analytical chemistry to explore these mechanisms comprehensively.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that improve hearing and quality of life for older adults.

How similar studies have gone: Previous research has shown promising results in understanding auditory processing and potential interventions for hearing loss, making this approach both relevant and potentially impactful.

Where this research is happening

  • University of Arizona
    Tucson, United States
    Active

Researchers

  • Principal investigator: Yamoah, Ebenezer N — University of Arizona
  • Study coordinator: Yamoah, Ebenezer N

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.