Understanding and reducing the harmful effects of internal radiation exposure.
Multi-Scale Evaluation and Mitigation of Toxicities Following Internal Radionuclide Contamination
This study looks at how radiation from certain substances can affect different parts of the body and aims to find better ways to protect patients from the harmful effects of radiation exposure.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11051906 on NIH RePORTER |
What this research studies
This research investigates how internal radionuclide contamination affects the body, focusing on the uneven distribution of radiation within organs and tissues. By analyzing the impact of various factors such as the chemical form of the radionuclide and the body's immune response, the study aims to improve dosimetry modeling and develop effective countermeasures. Patients may benefit from advancements in understanding how to mitigate the toxic effects of radiation exposure through innovative biomarker discovery and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have been exposed to radionuclides or are at risk of such exposure.
Not a fit: Patients who have not been exposed to radionuclides or do not have related health concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment options for patients exposed to internal radiation.
How similar studies have performed: Previous research has shown promise in understanding radiation effects, but this approach is innovative and aims to fill significant gaps in current knowledge.
Where this research is happening
Chicago, United States
- Northwestern University at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Woloschak, Gayle E. — Northwestern University at Chicago
- Study coordinator: Woloschak, Gayle E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.