Understanding and preventing youth-onset type 2 diabetes
The PRIORITY Study: from PRedIctiOn to pReventIon of youth-onset TYpe 2 diabetes
This study is looking at what causes type 2 diabetes in young people, especially those who might be more at risk, to help find better ways to predict who could develop the condition and how social factors play a role, all while working with trusted doctors to include kids from different backgrounds.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11052515 on NIH RePORTER |
What this research studies
This research focuses on identifying the risk factors and mechanisms that lead to youth-onset type 2 diabetes (YoT2D) in adolescents, particularly those from vulnerable populations. By studying early pubertal youth at risk for YoT2D, the research aims to develop better prediction methods for who may progress from prediabetes to diabetes. The study will also explore how social determinants of health impact these outcomes, utilizing trusted pediatric care providers to recruit participants from diverse backgrounds. This comprehensive approach seeks to address the urgent need for effective prevention strategies in at-risk youth.
Who could benefit from this research
Good fit: Ideal candidates for this research include adolescents aged 10 to 21 who are at risk for developing youth-onset type 2 diabetes, particularly those from racial and ethnic minority backgrounds.
Not a fit: Patients who are not adolescents or those who do not have risk factors for youth-onset type 2 diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies for youth-onset type 2 diabetes, ultimately reducing its prevalence and associated health complications.
How similar studies have performed: Previous research has shown success in understanding diabetes risk factors in youth, but this study aims to innovate by focusing on social determinants and specific vulnerable populations.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Magge, Sheela Natesh — Johns Hopkins University
- Study coordinator: Magge, Sheela Natesh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.