Understanding and preventing psychosis in at-risk individuals
ProNET: Psychosis-Risk Outcomes Network
This study is looking for ways to spot early signs of psychosis in people who are at high risk, using brain scans and smartphone data to help understand their behavior and thinking, so we can find better ways to prevent these disorders from developing.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10860939 on NIH RePORTER |
What this research studies
This research investigates individuals at high risk for developing psychosis, aiming to identify biological and behavioral markers that can help predict and prevent the onset of psychotic disorders. The study will involve detailed assessments of 1,040 participants across 26 international sites, utilizing advanced techniques such as MRI, EEG, and smartphone data collection to gather comprehensive information about brain function, cognition, and behavior. By mapping these biomarkers to clinical outcomes over a two-year period, the research seeks to enhance our understanding of psychosis risk and improve treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals identified as being at clinical high risk for psychosis.
Not a fit: Patients who are not at risk for psychosis or who have already developed psychotic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies and treatments for individuals at risk of developing psychosis.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for psychosis risk, but this approach aims to deepen understanding through a comprehensive, multi-modal analysis.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Woods, Scott W — Yale University
- Study coordinator: Woods, Scott W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.