Understanding and preventing malnutrition in infants with cleft lip and palate
Official title: Leveraging Data for Infants with Cleft to Grow and Flourish: The BLOOM Study
Funded at Seattle Children's Hospital · NIH-11142432 · Data updated 2026-11-12
This study is looking at how orofacial clefts in babies might lead to malnutrition, so we can find out what factors contribute to this and help doctors provide better care for these infants.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Seattle Children's Hospital NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | August 1, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $858,961 |
| NIH project number | 5R01DE033703-02 |
| Project ID | NIH-11142432 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are infants diagnosed with orofacial clefts, particularly those at risk of malnutrition.
✕Less likely to help
Patients without a diagnosis of orofacial clefts or those who are older than 11 years may not benefit from this research.
What this research studies
This research investigates the risk of malnutrition in infants born with orofacial clefts, a condition affecting over 5,000 infants annually in the U.S. The study will analyze data from a large cohort of infants to identify which factors contribute to undernutrition and how it affects health outcomes. By examining both caregiver and infant characteristics, the research aims to develop predictive models that can help healthcare providers intervene early and improve care coordination. The study will involve both retrospective and prospective analyses to gather comprehensive insights.
Why it matters
Potential benefit: If successful, this research could lead to improved nutritional outcomes and overall health for infants with clefts, enhancing their quality of life.
How similar studies have gone: Previous research has shown success in identifying risk factors for malnutrition in similar pediatric populations, indicating that this approach has potential for impactful findings.
Where this research is happening
-
Seattle Children's Hospital
Seattle, United States Active
Researchers
- Principal investigator: Mckinney, Christy Michelle — Seattle Children's Hospital
- Study coordinator: Mckinney, Christy Michelle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.