Understanding and preventing malnutrition in infants with cleft lip and palate

Leveraging Data for Infants with Cleft to Grow and Flourish: The BLOOM Study

NIH-funded research Seattle Children's Hospital · NIH-11142432

This study is looking at how orofacial clefts in babies might lead to malnutrition, so we can find out what factors contribute to this and help doctors provide better care for these infants.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSeattle Children's Hospital NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-11142432 on NIH RePORTER

What this research studies

This research investigates the risk of malnutrition in infants born with orofacial clefts, a condition affecting over 5,000 infants annually in the U.S. The study will analyze data from a large cohort of infants to identify which factors contribute to undernutrition and how it affects health outcomes. By examining both caregiver and infant characteristics, the research aims to develop predictive models that can help healthcare providers intervene early and improve care coordination. The study will involve both retrospective and prospective analyses to gather comprehensive insights.

Who could benefit from this research

Good fit: Ideal candidates for this research are infants diagnosed with orofacial clefts, particularly those at risk of malnutrition.

Not a fit: Patients without a diagnosis of orofacial clefts or those who are older than 11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved nutritional outcomes and overall health for infants with clefts, enhancing their quality of life.

How similar studies have performed: Previous research has shown success in identifying risk factors for malnutrition in similar pediatric populations, indicating that this approach has potential for impactful findings.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Airway infections
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.