Understanding and preventing liver cancer related to metabolic dysfunction
Data & Analysis Core
This study is looking at ways to help people with fatty liver disease avoid developing liver cancer by checking their health markers and trying out new prevention methods, so if you have this condition, your participation could help improve early diagnosis and treatment options.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10874543 on NIH RePORTER |
What this research studies
This research focuses on identifying risk factors and preventive strategies for hepatocellular carcinoma (HCC), particularly in patients with metabolic dysfunction associated fatty liver disease (MAFLD). It involves analyzing biochemical and genetic markers, as well as implementing chemoprevention and surveillance methods. The study will utilize data from a multicity cohort of individuals with MAFLD-related cirrhosis and will track patient outcomes to see if they develop HCC. By enhancing data collection and patient follow-up, the research aims to improve early diagnosis and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with metabolic dysfunction associated fatty liver disease (MAFLD) and cirrhosis.
Not a fit: Patients without metabolic dysfunction or liver disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and early detection strategies for liver cancer, potentially reducing mortality rates.
How similar studies have performed: Previous research has shown promise in understanding the links between metabolic dysfunction and liver cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Amos, Christopher I. — Baylor College of Medicine
- Study coordinator: Amos, Christopher I.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.