Understanding and Preventing Liver Cancer Linked to Metabolic Fatty Liver Disease

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NIH-funded research Baylor College of Medicine · NIH-11146354

This program aims to understand why some people get liver cancer from fatty liver disease and find ways to prevent it.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionBaylor College of Medicine NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11146354 on NIH RePORTER

What this research studies

This program is dedicated to understanding and preventing a type of liver cancer called hepatocellular carcinoma (HCC), especially when it's linked to metabolic dysfunction-associated fatty liver disease (MAFLD). We are looking into various factors like physical traits, blood markers, and genetic information to identify who might be at higher risk. The goal is to develop better ways to stop this cancer before it starts, including exploring new preventive treatments. This comprehensive effort brings together multiple projects and resources to tackle this serious health challenge.

Who could benefit from this research

Good fit: Patients with metabolic dysfunction-associated fatty liver disease (MAFLD) who are concerned about their risk of liver cancer may find this research relevant.

Not a fit: Patients whose liver cancer is not related to metabolic dysfunction or fatty liver disease may not directly benefit from this specific research focus.

Why it matters

Potential benefit: If successful, this work could lead to earlier identification of individuals at risk for liver cancer and new strategies to prevent its development.

How similar studies have performed: This program builds upon existing knowledge in liver cancer and metabolic disease, aiming to advance understanding and prevention in this specific area.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer BiologyCancer CenterDiabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.