Understanding and Preventing Liver Cancer from Fatty Liver Disease
Data & Analysis Core
This program aims to better understand and prevent liver cancer in people with fatty liver disease.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11146363 on NIH RePORTER |
What this research studies
Our program seeks to reduce deaths from liver cancer, especially for those with fatty liver disease (MAFLD). We are working to identify new risk factors, such as specific markers in the body and genetic traits, that contribute to liver cancer development. We also explore ways to prevent liver cancer, including potential medications and regular health screenings. This involves carefully collecting and analyzing patient information and samples from a large group of people with MAFLD-related cirrhosis across multiple cities, as well as using existing data from the Department of Veterans Affairs.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cirrhosis related to metabolic dysfunction-associated fatty liver disease (MAFLD).
Not a fit: Patients who do not have MAFLD-related cirrhosis may not directly benefit from this specific research program.
Why it matters
Potential benefit: If successful, this work could lead to improved ways to identify individuals at high risk and develop better strategies to prevent liver cancer in patients with fatty liver disease.
How similar studies have performed: This program builds upon an existing, ongoing prospective group of patients and retrospective data, suggesting a foundation of prior work in this area.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Amos, Christopher I. — Baylor College of Medicine
- Study coordinator: Amos, Christopher I.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.