Understanding and preventing early-onset colorectal cancer
PROSPECT: Pathways, Risk factors, and mOleculeS to Prevent Early-onset Colorectal Tumors
This study is looking into what causes colorectal cancer in people under 50, focusing on things like biology, environment, and lifestyle, to help find ways to prevent it and improve early detection for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Broad Institute, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-11047335 on NIH RePORTER |
What this research studies
This research investigates the complex factors that contribute to colorectal cancer in individuals under 50 years old. By examining biological, environmental, and lifestyle influences, the team aims to identify key risk factors and mechanisms that lead to cancer development. Utilizing advanced animal models and a collaborative approach, the research seeks to translate findings into effective prevention strategies. Patients may benefit from insights that could lead to earlier detection and intervention.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals under 50 years old who may be at risk for colorectal cancer due to genetic, environmental, or lifestyle factors.
Not a fit: Patients over 50 years old or those without risk factors for colorectal cancer may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new prevention strategies that significantly reduce the incidence of early-onset colorectal cancer.
How similar studies have performed: Previous research has shown promise in understanding risk factors for colorectal cancer, but this approach is innovative in its focus on early-onset cases.
Where this research is happening
Cambridge, United States
- Broad Institute, INC. — Cambridge, United States (Active)
Researchers
- Principal investigator: Huttenhower, Curtis — Broad Institute, INC.
- Study coordinator: Huttenhower, Curtis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.