Understanding and preventing brain changes in children with type 1 diabetes

Identifying Targets for Preventing Neurocognitive Complications in Youth with T1D

NIH-funded research Joslin Diabetes Center · NIH-11175443

This project looks at how type 1 diabetes affects brain health in young children and aims to find ways to protect their developing brains.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionJoslin Diabetes Center NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11175443 on NIH RePORTER

What this research studies

This project aims to understand how type 1 diabetes affects brain development in young children, a critical time for brain maturation. Researchers will follow children aged 4-8 years who have been recently diagnosed with type 1 diabetes. They will look for factors that might put children at risk for brain health issues or protect them. The goal is to gather information that could lead to new ways to prevent these complications and support healthy brain development.

Who could benefit from this research

Good fit: Ideal candidates are pre-pubertal children aged 4-8 years who have been recently diagnosed with type 1 diabetes.

Not a fit: Patients outside the specified age range or those not newly diagnosed with type 1 diabetes may not directly benefit from participating in this specific research.

Why it matters

Potential benefit: If successful, this work could lead to new ways to protect the developing brains of children with type 1 diabetes from potential complications.

How similar studies have performed: This project builds upon existing knowledge about type 1 diabetes and brain health, aiming to provide a more comprehensive understanding in young children.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Brittle Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.