Understanding and predicting irritability in children and adolescents
Official title: Multi-level mechanisms and predictors of irritability: An innovative approach bridging laboratory and real-world measures
Funded at Yale University · NIH-10909435 · Data updated 2026-11-12
This study is looking into what causes long-lasting irritability in kids and teens, helping us understand which young people might struggle with it so we can find better ways to support them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 4, 2024 |
| Project end | September 3, 2027 |
| Funding year | 2024 |
| Award (this year) | $1,507,500 |
| NIH project number | 1DP2MH140132-01 |
| Project ID | NIH-10909435 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children and adolescents aged 0-20 who exhibit signs of chronic irritability.
✕Less likely to help
Patients who do not experience irritability or have other unrelated psychiatric conditions may not benefit from this research.
What this research studies
This research investigates the causes and predictors of chronic irritability in children and adolescents, which can lead to significant emotional and behavioral issues. By examining various factors such as brain function, physiological responses, and social environments, the study aims to identify which young individuals are at risk for persistent irritability. The approach combines laboratory assessments with real-world data to create a comprehensive understanding of irritability's development. This innovative methodology seeks to fill the gap in effective treatments for chronic irritability.
Why it matters
Potential benefit: If successful, this research could lead to better identification and treatment strategies for children and adolescents suffering from chronic irritability.
How similar studies have gone: While there has been some research on irritability, this approach is innovative and aims to address gaps in understanding chronic irritability, making it a novel investigation.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Tseng, Wan-Ling — Yale University
- Study coordinator: Tseng, Wan-Ling
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.