Understanding and Predicting Basal-Like Breast Cancer Progression
Prognostic analysis and progression modeling of basal-like breast cancer using multi-region sequencing
This project aims to better understand how aggressive basal-like breast cancer grows and spreads, hoping to improve how we predict its course and treat it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Buffalo NIH-funded |
| Lab location | 1 site (Amherst, United States) |
| Project ID | NIH-11111304 on NIH RePORTER |
What this research studies
Basal-like breast cancer is a very aggressive type that affects many women, and currently, it's hard to predict how it will behave or to find effective targeted treatments. Most patients are considered high-risk, and often receive harsh chemotherapy because other options aren't available. Our goal is to use advanced genetic mapping of different areas within a tumor, combined with powerful computer analysis, to uncover the biological reasons this cancer progresses. This work could lead to better ways to tell how serious a patient's cancer is and guide doctors to more personalized treatments.
Who could benefit from this research
Good fit: This research is focused on understanding basal-like breast cancer, so patients with this specific type of breast cancer may eventually benefit from its findings.
Not a fit: Patients with other types of breast cancer or other conditions would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more accurate predictions of basal-like breast cancer's behavior and help doctors choose more effective, less harsh treatments for patients.
How similar studies have performed: This project builds upon previous work by the researchers, suggesting a foundation of prior success in related areas, but the specific approach may be novel.
Where this research is happening
Amherst, United States
- State University of New York at Buffalo — Amherst, United States (Active)
Researchers
- Principal investigator: Sun, Yijun — State University of New York at Buffalo
- Study coordinator: Sun, Yijun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.