NIH-funded research U01 cooperative agreement

Understanding and predicting bacterial infections in hospitals during COVID-19.

Official title: RFA-CK20-003: Analysis and Simulation of Bacterial Infections and Resource Strain in Hospitals during the COVID-19 Pandemic

Funded at Columbia University Health Sciences · NIH-11031920 · Data updated 2026-11-12

This study is looking at how to predict and manage infections that are resistant to antibiotics in hospitals, especially during the COVID-19 pandemic, so that doctors can better protect patients like you from these infections.

More COVID-19 research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences
NIH-funded
Lab location1 site (New York, United States)
Project startAugust 1, 2020
Project endJuly 31, 2025
Funding year2024
Award (this year)$258,328
NIH project number5U01CK000592-05
Project IDNIH-11031920 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include hospitalized patients who are at risk of acquiring antimicrobial-resistant infections.

Less likely to help

Patients who are not hospitalized or do not have a risk of infection from antimicrobial-resistant pathogens may not benefit from this research.

What this research studies

This research focuses on developing advanced models to simulate and forecast outbreaks of antimicrobial-resistant (AR) infections in hospitals, particularly during the COVID-19 pandemic. By analyzing hospitalization records and diagnostic data from major hospitals in New York City, the project aims to identify individual patient risks and optimal intervention strategies. The researchers will create two types of mathematical models: one that simulates infection dynamics across multiple healthcare facilities and another that tracks individual patient movements and infection status. This approach will help healthcare providers better manage and prevent healthcare-associated infections.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing and controlling bacterial infections in healthcare settings, ultimately enhancing patient safety.

How similar studies have gone: Other research has shown success in using mathematical modeling to predict infectious disease outbreaks, indicating that this approach has potential for impactful results.

Where this research is happening

  • Columbia University Health Sciences
    New York, United States
    Active

Researchers

  • Principal investigator: Shaman, Jeffrey L — Columbia University Health Sciences
  • Study coordinator: Shaman, Jeffrey L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.