Understanding and modifying how cells respond to redox signals
Decoding and Rewiring Enzymatic Redox Signal Transduction Pathways
This study is looking at how our cells notice and react to important signals that help keep them balanced, which could help people with health issues related to these signals, like certain diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10877065 on NIH RePORTER |
What this research studies
This research investigates how cells detect and respond to redox signals, which are crucial for various physiological processes. By exploring the specificity of these signaling pathways, the researchers aim to understand how to manipulate them to restore or disrupt cellular balance. The approach involves studying the mechanisms of reactive agents like nitric oxide and carbon monoxide, which play significant roles in health and disease. Patients may benefit from insights gained in this research, particularly those with conditions linked to redox imbalances.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from diseases associated with redox imbalances, including certain cancers and neurological disorders.
Not a fit: Patients with conditions unrelated to redox signaling or those who do not exhibit redox imbalances may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for diseases related to redox imbalances, such as cancer and neurological disorders.
How similar studies have performed: Previous research has shown promise in understanding redox signaling pathways, suggesting that this approach could yield significant advancements in treatment.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Bhagi, Ambika — University of Minnesota
- Study coordinator: Bhagi, Ambika
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.