Understanding and mapping cellular aging and senescence in human tissues
WU-SN-TMC Bio-Analysis Core
This study is looking at old cells in the body that can cause health problems as we age, and it aims to understand how these cells work so that we can find new ways to treat age-related diseases that might help patients feel better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10914212 on NIH RePORTER |
What this research studies
This research focuses on identifying and analyzing senescent cells, which are implicated in various human diseases. By utilizing advanced technologies, the team aims to create detailed atlases that map the behavior and characteristics of these cells across different tissues and stages of life. The goal is to develop robust methods for isolating and manipulating senescent cells, which could lead to new therapies for age-related diseases. Patients may benefit from insights gained through high-throughput analyses of biomarkers and cellular functions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals experiencing age-related conditions or diseases associated with cellular senescence.
Not a fit: Patients with acute conditions unrelated to aging or cellular senescence may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to novel therapies that target cellular senescence, potentially reversing or slowing down age-related diseases.
How similar studies have performed: Previous research has shown promise in targeting senescent cells in model organisms, indicating potential for success in human applications.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Chen, Feng — Washington University
- Study coordinator: Chen, Feng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.