Understanding and managing symptoms in cystic fibrosis
Official title: Advancing Symptom Science and Management in Cystic Fibrosis: Biological, Social, and Clinical Mechanisms
Funded at Emory University · NIH-11001476 · Data updated 2026-11-12
This study is looking to understand the different symptoms people with cystic fibrosis experience, like pain and fatigue, by talking to patients and analyzing their health information, so we can learn how their health and social situations affect their lives and care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | December 15, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $567,959 |
| NIH project number | 5R01HL171735-02 |
| Project ID | NIH-11001476 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are living with cystic fibrosis.
✕Less likely to help
Patients who are under 21 years old or do not have a diagnosis of cystic fibrosis may not benefit from this research.
What this research studies
This research aims to explore the complex symptoms experienced by individuals with cystic fibrosis (CF) by examining biological, social, and clinical factors. It will involve collecting patient-reported outcomes to identify patterns of symptoms such as pain and fatigue, and how these relate to social determinants of health. Additionally, the study will analyze biological samples to uncover metabolic signatures that may correlate with symptom experiences. Through surveys and interviews, the research will also gather insights into patients' experiences with CF care, aiming to create a comprehensive understanding of how these factors interact.
Why it matters
Potential benefit: If successful, this research could lead to improved symptom management and enhanced quality of life for individuals living with cystic fibrosis.
How similar studies have gone: Other research has shown success in understanding symptom management in chronic diseases, making this approach promising yet still innovative in the context of cystic fibrosis.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Kavalieratos, Dionysios — Emory University
- Study coordinator: Kavalieratos, Dionysios
Related research
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Pharmacogenomic Predictors of Clinical Responses in Cystic Fibrosis using Targeted WGS
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-
Ceftaroline-meropenem combo to beat MRSA in cystic fibrosis
A new combination antibiotic approach is being tested to help people with cystic fibrosis who have MRSA infections that resist standard treatments.
-
Gut microbiome in cystic fibrosis and colorectal cancer risk
Researchers are studying how the gut bacteria in adults with cystic fibrosis influence the development of colorectal cancer.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.