NIH-funded research R01 grant

Understanding and managing postoperative pain better.

Official title: Robust Computational and Data Analytic Tools for In-depth Understanding Postoperative Pain Mechanism with Enhanced Pain Management and Clinical Decision Making

Funded at Univ of North Carolina Chapel Hill · NIH-10773526 · Data updated 2026-11-12

This study is looking at new ways to understand and manage pain after surgery, so that patients can get more personalized care and feel better during their recovery.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startSeptember 13, 2024
Project endAugust 31, 2028
Funding year2024
Award (this year)$488,419
NIH project number1R01LM014407-01
Project IDNIH-10773526 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals who are scheduled for surgical procedures and may experience postoperative pain.

Less likely to help

Patients who are not undergoing surgery or those with chronic pain unrelated to surgical procedures may not benefit from this research.

What this research studies

This research focuses on developing advanced computational and data analytic tools to gain a deeper understanding of the mechanisms behind postoperative pain. By analyzing various data sources and employing sophisticated models, the project aims to enhance pain management strategies and improve clinical decision-making for patients recovering from surgery. Patients may benefit from more personalized pain management approaches based on their unique pain profiles and responses to analgesic treatments.

Why it matters

Potential benefit: If successful, this research could lead to more effective pain management strategies for patients after surgery.

How similar studies have gone: Previous research has shown promise in using computational tools to analyze pain mechanisms, indicating that this approach could yield significant insights.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Zou, Baiming — Univ of North Carolina Chapel Hill
  • Study coordinator: Zou, Baiming

Related research

Other NIH-funded projects on the same topics.

  • Better Predicting and Personalizing Postoperative Pain Care

    Aimed at using advanced data tools to better predict and manage a patient’s pain after surgery and reduce opioid-related risks.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11398952

  • Better prediction and personalized control of pain after surgery

    This project builds computer tools to predict who will have bad pain after surgery and help doctors tailor pain control for patients recovering from operations.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11192819

  • Using virtual reality and biofeedback to manage pain after surgery in kids

    This study is exploring a fun new way to help kids and teens feel better after surgery by using virtual reality and biofeedback, so they can manage their pain on their own and recover more comfortably.

    NIH research Nemours Children's Hospital, Delaware · Wilmington, United States · NIH-11044480

  • Using advanced computer tools to improve pain management after surgery

    This study is looking at how to make pain relief after surgery better by using smart computer tools to understand patient records, so we can find out who might need different kinds of pain management to feel their best while they recover.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-10684876

  • Understanding how octopuses integrate sensory information and make decisions

    This study is exploring how octopuses use their arms to grip things by looking closely at their nervous system and movements, which could help us understand their amazing abilities better.

    NIH research Michigan State University · East Lansing, United States · NIH-9949982

  • NoviGuide for Newborn Care in Pakistan

    A small NIH grant to test a pocket-sized decision support tool for nurses and doctors to improve newborn care in Pakistan.

    NIH research Aga Khan University (Pakistan) · Karachi, Pakistan · NIH-11624823

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.