Understanding and managing musculoskeletal pain
Official title: Chicago Center on Musculoskeletal Pain (C-COMP) (Overall Application)
Funded at Rush University Medical Center · NIH-10892120 · Data updated 2026-11-12
This study is looking into how we can better understand and manage pain from musculoskeletal and rheumatic diseases, with the goal of finding safer and more effective treatments that can help patients feel better.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rush University Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | September 14, 2021 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $761,693 |
| NIH project number | 5P30AR079206-04 |
| Project ID | NIH-10892120 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals experiencing chronic musculoskeletal pain or related rheumatic conditions.
✕Less likely to help
Patients with acute pain conditions or those not affected by musculoskeletal or rheumatic diseases may not benefit from this research.
What this research studies
This research focuses on exploring the mechanisms behind pain related to musculoskeletal and rheumatic diseases. By establishing a center dedicated to this area, the project aims to integrate various fields of expertise to improve pain management strategies. The research will involve both basic and clinical approaches to identify new targets for analgesic drugs, addressing the limitations of current pain relief options. Patients may benefit from advancements in treatment options that are safer and more effective.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies for patients suffering from musculoskeletal pain.
How similar studies have gone: Previous research in similar areas has shown promise in understanding pain mechanisms, suggesting that this approach could yield significant advancements.
Where this research is happening
-
Rush University Medical Center
Chicago, United States Active
Researchers
- Principal investigator: Malfait, Anne-Marie — Rush University Medical Center
- Study coordinator: Malfait, Anne-Marie
Related research
Other NIH-funded projects on the same topics.
-
mHealth tool to boost physical therapy outcomes for adults with musculoskeletal pain
A mobile health app is being tested to help adults in physical therapy stay on track with home exercises and improve pain and function.
-
Biopsychosocial factors in pediatric chronic musculoskeletal pain
A study at Cincinnati Children’s Hospital will look at how biological, psychological, and social factors contribute to chronic muscle and joint pain in young people to find better ways to help them.
-
Nonaddictive pain-relief prodrug gel for joint and musculoskeletal pain
A new, nonaddictive pain-relief gel uses a hydromorphone prodrug that stays at the site of pain to reduce pain without strong addiction risk.
-
Neurobiological and psychosocial factors that may turn acute teen pain into chronic pain
A study following teenagers with acute musculoskeletal pain to understand why some develop chronic pain and how biology and psychology interact to shape their outcomes.
-
Tech-guided walking plus Tai Chi to improve function for veterans with COPD and chronic pain
This program helps veterans with COPD and long-term muscle or joint pain use a web-based step program together with Tai Chi to move more and feel stronger.
-
Resilience Coaching for Teens with Long-Lasting Muscle and Bone Pain
This project offers resilience coaching to help teenagers manage ongoing muscle and bone pain and improve their well-being.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.