Understanding and managing eye pressure in healthy and glaucoma eyes
Continuous measurement and control of intraocular pressure in normal and glaucomatous eyes
This work explores how eye pressure is naturally controlled and how it changes throughout the day in people with and without glaucoma.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Florida NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-11134120 on NIH RePORTER |
What this research studies
Our eyes have a natural pressure, called intraocular pressure (IOP), which is important for eye health. In conditions like glaucoma, this pressure can become too high and damage vision. We are learning more about how the body's automatic systems and daily rhythms, like sleep-wake cycles, affect IOP. This understanding could help us develop better ways to diagnose and treat glaucoma, a leading cause of irreversible blindness. We are using advanced tools to continuously measure eye pressure to see how these factors influence it.
Who could benefit from this research
Good fit: This foundational work is relevant to individuals with glaucoma or those at risk of developing the condition.
Not a fit: Patients not affected by glaucoma or conditions related to intraocular pressure regulation may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new insights into glaucoma development and improved strategies for its diagnosis and treatment.
How similar studies have performed: While continuous IOP measurement in animals has been conducted, this work aims to provide novel insights into the role of daily IOP fluctuations in eye function.
Where this research is happening
Tampa, United States
- University of South Florida — Tampa, United States (Active)
Researchers
- Principal investigator: Passaglia, Christopher L — University of South Florida
- Study coordinator: Passaglia, Christopher L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.