NIH-funded research R21 grant

Understanding and influencing brain activity patterns related to attention and mood disorders

Official title: Characterizing and manipulating large-scale activity in the brain

Funded at Emory University · NIH-11117994 · Data updated 2026-11-12

This study is looking at how certain brain activity patterns are connected to attention and mood issues like ADHD and depression, with the goal of finding new ways to help people improve their focus and manage their emotions better.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionEmory University
NIH-funded
Lab location1 site (Atlanta, United States)
Project startMay 1, 2025
Project endApril 30, 2027
Funding year2025
Award (this year)$417,200
NIH project number1R21MH140191-01
Project IDNIH-11117994 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals diagnosed with attention deficit hyperactivity disorder (ADHD) or major depressive disorder (MDD).

Less likely to help

Patients without attention or mood disorders may not receive any benefit from this research.

What this research studies

This research investigates how specific patterns of brain activity, known as quasiperiodic patterns (QPPs), are linked to attention and mood disorders like ADHD and major depressive disorder. Using advanced imaging techniques, the study aims to identify and manipulate these brain activity patterns to better understand their role in these conditions. By exploring how these patterns can be altered, the research seeks to develop potential therapeutic interventions that could improve focus and emotional regulation in affected individuals.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that enhance attention and mood regulation for patients with ADHD and major depressive disorder.

How similar studies have gone: Previous research has shown promise in manipulating brain activity patterns, suggesting that this approach could yield valuable insights and therapeutic options.

Where this research is happening

  • Emory University
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Keilholz, Shella D — Emory University
  • Study coordinator: Keilholz, Shella D

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.