Understanding and improving treatments for sickle cell disease

"REAL Answers" (Registry Expansion Analyses to Learn)

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-10908994

This study is looking for people with sickle cell disease to help us learn more about different treatments and find the best ways to manage the condition, so your experiences can help improve care for everyone with SCD.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10908994 on NIH RePORTER

What this research studies

This research focuses on sickle cell disease (SCD), a genetic blood disorder that primarily affects individuals of African descent. It aims to expand a registry to analyze various treatment options and their effectiveness for different subtypes of SCD. By collecting and examining data from patients, the research seeks to identify the best therapeutic approaches and combinations to manage the disease more effectively. Patients will be involved in providing information that can help shape future treatment guidelines.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with sickle cell disease, particularly those of African descent.

Not a fit: Patients with other blood disorders or those not diagnosed with sickle cell disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective treatment options for patients with sickle cell disease.

How similar studies have performed: Previous research has shown success in improving treatment outcomes for sickle cell disease through the use of disease-modifying therapies, indicating that this approach has potential.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.