Understanding and improving treatments for sickle cell disease
Official title: "REAL Answers" (Registry Expansion Analyses to Learn)
Funded at Icahn School of Medicine at Mount Sinai · NIH-10908994 · Data updated 2026-11-12
This study is looking for people with sickle cell disease to help us learn more about different treatments and find the best ways to manage the condition, so your experiences can help improve care for everyone with SCD.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 20, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $2,389,467 |
| NIH project number | 5U01HL167036-02 |
| Project ID | NIH-10908994 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with sickle cell disease, particularly those of African descent.
✕Less likely to help
Patients with other blood disorders or those not diagnosed with sickle cell disease may not benefit from this research.
What this research studies
This research focuses on sickle cell disease (SCD), a genetic blood disorder that primarily affects individuals of African descent. It aims to expand a registry to analyze various treatment options and their effectiveness for different subtypes of SCD. By collecting and examining data from patients, the research seeks to identify the best therapeutic approaches and combinations to manage the disease more effectively. Patients will be involved in providing information that can help shape future treatment guidelines.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment options for patients with sickle cell disease.
How similar studies have gone: Previous research has shown success in improving treatment outcomes for sickle cell disease through the use of disease-modifying therapies, indicating that this approach has potential.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Glassberg, Jeffrey Avins — Icahn School of Medicine at Mount Sinai
- Study coordinator: Glassberg, Jeffrey Avins
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.