NIH-funded research NIH-funded research

Understanding and improving treatments for jaw pain disorders

Official title: TMJ SYMPHONY Systems-integrated model and mechanisms of patient-centered holistic outcomes and network-supported training and therapy

Funded at Clemson University · NIH-10829112 · Data updated 2026-11-12

This study is looking at how different factors affect jaw pain for people with temporomandibular disorders (TMD), especially women, to create better, personalized treatment options that can help them feel better.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionClemson University
NIH-funded
Lab location1 site (Clemson, United States)
Project startSeptember 14, 2023
Project endSeptember 13, 2025
Funding year2023
Award (this year)$384,392
NIH project number1R34DE033593-01
Project IDNIH-10829112 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals experiencing temporomandibular disorders, particularly those who have not found relief through conventional treatments.

Less likely to help

Patients with jaw pain not related to temporomandibular disorders may not benefit from this research.

What this research studies

This research focuses on temporomandibular disorders (TMDs), which affect millions of people, particularly women. It aims to uncover the complex interactions between the structure and function of the jaw joint, pain perception, and various biological and psychosocial factors. By utilizing a multidisciplinary approach that includes computational models and human studies, the project seeks to develop personalized treatment guidelines and improve therapeutic outcomes for patients suffering from TMD.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatments for individuals suffering from temporomandibular disorders.

How similar studies have gone: Previous research has shown promise in understanding TMD through multidisciplinary approaches, indicating potential for success in this novel investigation.

Where this research is happening

  • Clemson University
    Clemson, United States
    Active

Researchers

  • Principal investigator: Yao, Hai — Clemson University
  • Study coordinator: Yao, Hai

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.