Understanding and improving treatments for food allergies
Official title: Therapeutic and Mechanistic Insights in Food Allergy
Funded at Stanford University · NIH-11059992 · Data updated 2026-11-12
This study is looking at a way to help people with food allergies feel safer by testing if taking allergenic foods less often can still help them build tolerance, making it easier for those who find daily treatments tough to manage.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | March 21, 2024 |
| Project end | February 28, 2031 |
| Funding year | 2025 |
| Award (this year) | $380,000 |
| NIH project number | 5U01AI182039-02 |
| Project ID | NIH-11059992 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with food allergies who have participated in oral immunotherapy trials.
✕Less likely to help
Patients with food allergies who have not undergone any form of oral immunotherapy may not benefit from this research.
What this research studies
This research focuses on food allergies, which affect millions of people and can lead to severe reactions. It investigates oral immunotherapy (OIT), a treatment where patients gradually consume increasing amounts of allergenic foods to build tolerance. The study aims to explore whether less frequent dosing can maintain desensitization to allergens, addressing challenges faced by patients who struggle with daily dosing and its associated complications. By analyzing long-term outcomes from previous OIT trials, the research seeks to develop more manageable treatment options for patients.
Why it matters
Potential benefit: If successful, this research could lead to more effective and less burdensome treatment options for individuals with food allergies.
How similar studies have gone: Previous research on oral immunotherapy has shown promise, but this specific approach to less frequent dosing is novel and untested.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Sindher, Sayantani B. — Stanford University
- Study coordinator: Sindher, Sayantani B.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.