Understanding and improving treatments for atrial fibrillation
Electrophysiology Scientific Core 2
This study is looking into the causes of atrial fibrillation, a heart rhythm problem that can lead to strokes, to find better ways to prevent and treat it, using heart tests and cell studies to discover new treatment options.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10896379 on NIH RePORTER |
What this research studies
This research focuses on atrial fibrillation (AF), a common heart rhythm disorder that increases the risk of stroke and cardiovascular issues. The team aims to uncover the genetic and molecular mechanisms behind AF to develop better prevention and treatment strategies. They will collect and analyze ECG data, perform optical mapping on heart tissues, and study isolated heart cells to understand how AF progresses and how it can be effectively managed. By linking cellular changes to AF mechanisms, the research seeks to identify new therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with atrial fibrillation, especially those affected by obesity or age-related factors.
Not a fit: Patients without atrial fibrillation or those with other unrelated cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatments for patients with atrial fibrillation.
How similar studies have performed: Previous research has shown promise in understanding atrial fibrillation through genetic and electrophysiological approaches, indicating potential for success in this area.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Laurita, Kenneth — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Laurita, Kenneth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.