Understanding and improving treatment for systemic sclerosis vasculopathy
Official title: Systemic sclerosis (SSc) vasculopathy: Improved clinical monitoring and treatment
Funded at Veterans Health Administration · NIH-11044090 · Data updated 2026-11-12
This study is looking at how systemic sclerosis affects blood vessels, especially in the digestive system, to find better ways to monitor and treat patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | January 1, 2022 |
| Project end | December 31, 2026 |
| Funding year | 2025 |
| NIH project number | 5I01CX002111-05 |
| Project ID | NIH-11044090 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with systemic sclerosis, particularly those experiencing vascular complications.
✕Less likely to help
Patients with other autoimmune diseases that do not involve vascular dysfunction may not benefit from this research.
What this research studies
This research focuses on systemic sclerosis (SSc), a complex autoimmune disease that severely affects blood vessels and can lead to significant health complications. The study aims to investigate the underlying mechanisms of vascular dysfunction in SSc, particularly how it impacts the gastrointestinal tract. By conducting human studies, the researchers hope to identify effective clinical monitoring and treatment strategies to improve patient outcomes. The research builds on previous findings that highlighted the critical role of endothelial dysfunction in SSc.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment options for patients suffering from systemic sclerosis.
How similar studies have gone: Previous research has shown promising results in understanding vascular dysfunction in systemic sclerosis, indicating that this approach has potential for success.
Where this research is happening
-
Veterans Health Administration
Nashville, United States Active
Researchers
- Principal investigator: Frech, Tracy Minan — Veterans Health Administration
- Study coordinator: Frech, Tracy Minan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.