Understanding and improving treatment for obstructive sleep apnea
Project 3
['FUNDING_P01'] · BETH ISRAEL DEACONESS MEDICAL CENTER · NIH-10897858
This study is looking into how our bodies handle high carbon dioxide levels during sleep without waking us up, which could help create better treatments for people with obstructive sleep apnea, so they can breathe easier and sleep better.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BETH ISRAEL DEACONESS MEDICAL CENTER (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10897858 on ClinicalTrials.gov |
What this research studies
This research investigates obstructive sleep apnea (OSA), a common sleep disorder that causes breathing interruptions during sleep. The project aims to explore the underlying mechanisms of how the body responds to increased carbon dioxide levels without causing awakenings, which can disrupt sleep. By studying specific brain circuits and their roles in respiratory and cortical arousals, the research seeks to develop new treatment strategies that enhance breathing without increasing sleep disturbances. Patients may benefit from improved therapies that address the root causes of OSA and its associated health risks.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with obstructive sleep apnea who experience significant sleep disruptions and related health issues.
Not a fit: Patients without a diagnosis of obstructive sleep apnea or those whose condition is not significantly impacting their health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for obstructive sleep apnea, reducing its negative impact on patients' health and quality of life.
How similar studies have performed: Previous research has shown promise in understanding the mechanisms of sleep apnea, but this specific approach to enhancing ventilatory responses without increasing arousability is relatively novel.
Where this research is happening
BOSTON, UNITED STATES
- BETH ISRAEL DEACONESS MEDICAL CENTER — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FULLER, PATRICK M — BETH ISRAEL DEACONESS MEDICAL CENTER
- Study coordinator: FULLER, PATRICK M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.