Understanding and improving the body's ability to manage pain
Mechanisms and Modification of Pain Modulatory Capacity
['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-10840813
This study is looking at how chronic pain, especially in people with fibromyalgia, affects daily life and whether we can help improve the body's natural ability to manage pain without using opioids, so that those suffering can find better ways to cope.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-10840813 on ClinicalTrials.gov |
What this research studies
This research investigates how chronic pain affects individuals and explores the body's natural ability to modulate pain, known as pain modulatory capacity (PMC). It aims to identify psychological, behavioral, and neural mechanisms that contribute to chronic pain and tests whether these mechanisms can be trained or improved. The study focuses on patients with fibromyalgia, who may have a reduced ability to manage pain, and seeks to develop alternative treatments that do not rely on opioids. By understanding and enhancing PMC, the research hopes to provide new strategies for pain management.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from chronic pain conditions, particularly those diagnosed with fibromyalgia.
Not a fit: Patients with acute pain conditions or those not experiencing chronic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that improve pain management and reduce reliance on opioid medications for patients with chronic pain.
How similar studies have performed: Other research has shown promise in enhancing pain modulatory capacity through various interventions, indicating that this approach could be effective.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BISHOP, MARK D. — UNIVERSITY OF FLORIDA
- Study coordinator: BISHOP, MARK D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Diffuse Myofascial Pain Syndrome, Fibromyositis-Fibromyalgia Syndrome, MPD syndrome, fibromyalgia syndrome, myofascial pain dysfunction syndrome