Understanding and improving symptoms of lower urinary tract dysfunction
LURN II: Enhanced Characterization of Patients with LUTS Using Biopsychosocial Approaches
This study is looking to better understand lower urinary tract symptoms (LUTS) by grouping patients with similar experiences and finding new ways to measure these symptoms, while also exploring biological samples to identify potential markers that could help distinguish between different types of patients.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11122742 on NIH RePORTER |
What this research studies
This research aims to enhance our understanding of lower urinary tract symptoms (LUTS) by identifying distinct patient subtypes and improving how these symptoms are measured. It utilizes a consensus clustering approach based on self-reported data from patients, which helps in recognizing novel clusters of LUTS that are clinically relevant. Additionally, the study will analyze biological samples to uncover potential protein biomarkers that could differentiate between various subgroups of patients. By integrating patient experiences with clinical data, the research seeks to provide a more comprehensive view of LUTS.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing lower urinary tract symptoms, regardless of severity.
Not a fit: Patients without any symptoms of lower urinary tract dysfunction are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized treatment options for patients suffering from lower urinary tract symptoms.
How similar studies have performed: Previous research within the LURN network has shown promise in identifying patient subtypes and improving symptom measurement, indicating a foundation for continued success.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Griffith, James William — University of Chicago
- Study coordinator: Griffith, James William
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.