Understanding and Improving Recovery from Common Muscle and Joint Injuries
Biomarkers of Tissue Tolerance and Behavior in a Rat Model
['FUNDING_R01'] · TEMPLE UNIV OF THE COMMONWEALTH · NIH-11110472
This research explores new ways to help people recover from common muscle and joint injuries by looking at how activity, sleep, and aging affect these conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TEMPLE UNIV OF THE COMMONWEALTH (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-11110472 on ClinicalTrials.gov |
What this research studies
Many people suffer from ongoing muscle and joint pain, often called musculoskeletal injuries (MSKIs), which can be hard to treat. This project aims to understand why these injuries become chronic by looking at several factors. We are exploring if different types of physical activity, how injuries change over time, and differences related to sex and aging play a role. We also believe that poor sleep and tissue scarring might be key reasons why these injuries don't heal well.
Who could benefit from this research
Good fit: This foundational research is for anyone interested in the underlying causes and potential non-drug treatments for chronic muscle and joint injuries.
Not a fit: Patients seeking immediate clinical treatment or direct participation in a human trial would not directly benefit from this specific animal model research.
Why it matters
Potential benefit: If successful, this work could lead to new non-drug treatments, like better sleep strategies and specific exercise plans, to reduce pain and improve recovery from chronic muscle and joint injuries.
How similar studies have performed: This project takes a fresh approach by focusing on factors like sleep and tissue fibrosis, which are promising but less explored in the context of chronic musculoskeletal injuries.
Where this research is happening
PHILADELPHIA, UNITED STATES
- TEMPLE UNIV OF THE COMMONWEALTH — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BARBE, MARY F — TEMPLE UNIV OF THE COMMONWEALTH
- Study coordinator: BARBE, MARY F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.