Understanding and improving memory processes through real-time brain activity manipulation

Real-time manipulations to understand and improve memory processes

['FUNDING_OTHER'] · UNIVERSITY OF WASHINGTON · NIH-11021081

This study looks at how a part of the brain called the hippocampus helps us remember things by replaying our experiences during sleep and quiet moments, especially as we get older, to find ways to improve memory and keep our minds sharp.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF WASHINGTON (nih funded)
Locations1 site (SEATTLE, UNITED STATES)
Trial IDNIH-11021081 on ClinicalTrials.gov

What this research studies

This research investigates how the hippocampus, a brain region essential for memory, replays past experiences during sleep and pauses in activity. By examining this replay process, the study aims to understand how it influences decision-making and memory recall, particularly as people age. The researchers will use advanced techniques to manipulate and observe brain activity in real-time, providing insights into how memory functions and declines with age. The ultimate goal is to identify new therapeutic strategies to enhance memory and prevent cognitive decline.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults experiencing memory decline or cognitive impairment.

Not a fit: Patients with no memory issues or those who are not experiencing age-related cognitive changes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that improve memory and cognitive function in aging individuals.

How similar studies have performed: Previous research has shown promising results in understanding memory processes through similar approaches, indicating potential for success in this area.

Where this research is happening

SEATTLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.