Understanding and improving how nerve cells work in diseases.

TriMED: Measuring, Modeling and Manipulating Excitability and Disease

['FUNDING_TRAINING'] · WASHINGTON UNIVERSITY · NIH-10881878

This study is looking at how nerve cells work and how changes in tiny particles called ions can affect conditions like movement disorders, migraines, and epilepsy, with the goal of helping researchers find better treatments for these issues.

Quick facts

Phase['FUNDING_TRAINING']
Study typeNih_funding
SexAll
SponsorWASHINGTON UNIVERSITY (nih funded)
Locations1 site (SAINT LOUIS, UNITED STATES)
Trial IDNIH-10881878 on ClinicalTrials.gov

What this research studies

This research focuses on the electrical properties of nerve cells and how they are affected by ion transport, which is crucial for cell regulation. It aims to train researchers to explore the role of ion channels in various neurological diseases, such as movement disorders, migraines, and epilepsy. By combining advanced techniques in membrane biology, electrophysiology, and computational modeling, the project seeks to develop new therapies that can better manage these conditions. Patients may benefit from improved understanding and treatment options for diseases linked to ion transport dysfunction.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from neurological disorders like epilepsy, migraines, or movement disorders.

Not a fit: Patients with conditions unrelated to ion transport or those not affected by neurological disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapies for neurological diseases caused by ion transport issues.

How similar studies have performed: Other research has shown promising results in understanding ion channels and their role in neurological diseases, indicating that this approach has potential for success.

Where this research is happening

SAINT LOUIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Disease, Disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.