Understanding and improving how nerve cells work in diseases.
Official title: TriMED: Measuring, Modeling and Manipulating Excitability and Disease
Funded at Washington University · NIH-10881878 · Data updated 2026-11-12
This study is looking at how nerve cells work and how changes in tiny particles called ions can affect conditions like movement disorders, migraines, and epilepsy, with the goal of helping researchers find better treatments for these issues.
Quick facts
| Grant type | Training grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | July 5, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $312,304 |
| NIH project number | 5T32NS126120-02 |
| Project ID | NIH-10881878 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from neurological disorders like epilepsy, migraines, or movement disorders.
✕Less likely to help
Patients with conditions unrelated to ion transport or those not affected by neurological disorders may not benefit from this research.
What this research studies
This research focuses on the electrical properties of nerve cells and how they are affected by ion transport, which is crucial for cell regulation. It aims to train researchers to explore the role of ion channels in various neurological diseases, such as movement disorders, migraines, and epilepsy. By combining advanced techniques in membrane biology, electrophysiology, and computational modeling, the project seeks to develop new therapies that can better manage these conditions. Patients may benefit from improved understanding and treatment options for diseases linked to ion transport dysfunction.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for neurological diseases caused by ion transport issues.
How similar studies have gone: Other research has shown promising results in understanding ion channels and their role in neurological diseases, indicating that this approach has potential for success.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Nichols, Colin G — Washington University
- Study coordinator: Nichols, Colin G
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.