NIH-funded research U01 cooperative agreement

Understanding and improving healthy aging for World Trade Center responders

Official title: Promoting healthy aging among WTC responders: Frailty trajectories and intervention strategies

Funded at Icahn School of Medicine at Mount Sinai · NIH-10848178 · Data updated 2026-11-12

This study is looking at the health of World Trade Center responders as they age, especially to see who might be at risk for becoming frail, and it aims to find ways to help improve their quality of life.

More Aging research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai
NIH-funded
Lab location1 site (New York, United States)
Project startJuly 1, 2022
Project endJune 30, 2026
Funding year2024
Award (this year)$599,563
NIH project number5U01OH012473-03
Project IDNIH-10848178 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are World Trade Center responders aged 65 and over who may be experiencing signs of frailty.

Less likely to help

Patients who are not WTC responders or those who are younger than 65 may not benefit from this research.

What this research studies

This research focuses on the aging of World Trade Center (WTC) responders, particularly those who are now at risk for frailty and other aging-related conditions. The team has developed a specific frailty assessment tool to evaluate the health of these responders, aiming to identify those at higher risk for adverse health outcomes. By systematically assessing frailty and its consequences, the research seeks to implement intervention strategies that can enhance the quality of life for these aging individuals. The study will involve collecting data on physical measures and functional impairments to better understand the needs of this population.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes and quality of life for aging WTC responders.

How similar studies have gone: Similar research has shown success in assessing frailty in aging populations, indicating that this approach could be beneficial for WTC responders as well.

Where this research is happening

  • Icahn School of Medicine at Mount Sinai
    New York, United States
    Active

Researchers

  • Principal investigator: Ko, Fred Chau-Yang — Icahn School of Medicine at Mount Sinai
  • Study coordinator: Ko, Fred Chau-Yang

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.