NIH-funded research NIH-funded research

Understanding and improving health for people with type 2 heart attacks

Official title: Improving the Health Status of Individuals with Type 2 Myocardial Infarction

Funded at Massachusetts General Hospital · NIH-10903727 · Data updated 2026-11-12

This study is looking at how people who have type 2 heart attacks feel compared to those with type 1 heart attacks, and it wants to hear from both patients and doctors about how helpful exercise programs can be for recovery, with the goal of improving care for everyone affected by heart issues.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startAugust 9, 2023
Project endJuly 31, 2028
Funding year2024
Award (this year)$196,384
NIH project number5K23HL167659-02
Project IDNIH-10903727 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who have experienced a type 2 myocardial infarction, particularly older adults with multiple health conditions.

Less likely to help

Patients who have experienced type 1 myocardial infarctions or those without a history of heart attacks may not benefit from this research.

What this research studies

This research focuses on individuals who experience type 2 myocardial infarctions, which occur due to an imbalance in oxygen supply and demand in the heart. The study aims to explore the differences in health status between patients with type 2 and type 1 heart attacks, as well as to gather insights from patients and healthcare providers about the benefits and acceptance of cardiac rehabilitation. By increasing the use of exercise-based rehabilitation, which is effective for type 1 heart attacks, the research seeks to improve outcomes for those affected by type 2 heart attacks. The methodology includes collecting patient-reported data and clinician feedback to inform future treatment strategies.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes and quality of life for patients who have experienced type 2 myocardial infarctions.

How similar studies have gone: While exercise-based cardiac rehabilitation has shown success for type 1 myocardial infarctions, the application of such strategies for type 2 myocardial infarctions is less explored, making this research relatively novel.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Mccarthy, Cian Patrick — Massachusetts General Hospital
  • Study coordinator: Mccarthy, Cian Patrick

Related research

Other NIH-funded projects on the same topics.

  • Microglia Help Finish Seizures and Heal the Brain

    Scientists are studying how brain immune cells (microglia) help end severe seizures and repair brain damage, with potential new ideas for people who have had status epilepticus.

    NIH research University of Virginia · Charlottesville, United States · NIH-11607998

  • A decentralized, post-incarceration program to help people living with or at risk for HIV

    A patient-facing program called DEST2nation aims to help people recently released from jail or prison stay on HIV treatment (ART) and prevention (PrEP) by coordinating care, housing, and support services through peers and community organizations.

    NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11571401

  • Anti-inflammatory signaling of a key protein in heart attack recovery

    A study in people who have had a heart attack is exploring how a macrophage protein called Tristetraprolin may reduce inflammation and help protect heart tissue.

    NIH research University of Hawaii at Manoa · Honolulu, United States · NIH-11539056

  • Healer-initiated HIV testing to bridge gaps in South Africa

    This project tests whether traditional healers can offer HIV counseling and testing to people who don’t usually get tested, to link more individuals to care.

    NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11535016

  • How childhood nutrition affects health, thinking, and life outcomes by middle age

    This project compares people who got extra nutrition as children with those who did not to understand differences in health, thinking, and life outcomes in middle age.

    NIH research Emory University · Atlanta, United States · NIH-11515104

  • HER2 in breast cancer among diverse communities

    This project looks at genetic and molecular factors linked to HER2-positive breast cancer in women from Hispanic/Latina, Asian American/Pacific Islander, Indigenous American, African, and other diverse backgrounds.

    NIH research University of California at Davis · Davis, United States · NIH-11512975

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.