Understanding and improving healing of diabetic foot ulcers
Official title: University of Michigan Data Coordinating Center for the Diabetic Foot Consortium
Funded at University of Michigan at Ann Arbor · NIH-11012894 · Data updated 2026-11-12
This study is looking for ways to better predict how diabetic foot ulcers heal and to help prevent them from coming back, so if you have diabetes and have dealt with these ulcers, your participation could really help improve future treatments!
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | July 1, 2019 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $3,790,120 |
| NIH project number | 5U24DK122927-07 |
| Project ID | NIH-11012894 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with diabetes who are experiencing or at risk of developing diabetic foot ulcers.
✕Less likely to help
Patients without diabetes or those who do not have diabetic foot ulcers may not benefit from this research.
What this research studies
This research focuses on diabetic foot ulcers (DFUs), which are serious complications of diabetes that can lead to significant health issues. The Diabetic Foot Consortium aims to identify biomarkers that can help predict healing and prevent the recurrence of these ulcers. By collaborating with multiple clinical research units and utilizing advanced statistical methods, the project seeks to gather and analyze data on patient and physician characteristics that influence DFU outcomes. Patients may have the opportunity to contribute biospecimens for future studies, enhancing our understanding of this condition.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and preventive strategies for diabetic foot ulcers, enhancing patient quality of life.
How similar studies have gone: Previous research has shown promise in identifying biomarkers for chronic wounds, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Spino, Catherine a — University of Michigan at Ann Arbor
- Study coordinator: Spino, Catherine a
Related research
Other NIH-funded projects on the same topics.
-
Improving Diabetic Foot Ulcer Offloading with User-Friendly Cast Walker Design
A small pilot study to see how different removable cast walker designs affect daily use and healing of diabetic foot ulcers.
-
Home-based exercise to help Veterans recover after healed diabetic foot ulcers
A home-based exercise program for Veterans who recently healed from a diabetic foot ulcer to improve walking and daily function.
-
How Medicaid Coverage Changes Diabetic Foot Care in Safety-Net Patients
This project looks at how new Medicaid coverage in California affects foot care, ED visits, and outcomes for adults with diabetes in safety-net populations.
-
Multi-targeted approach to help heal diabetic foot ulcers using electric fields and nitric oxide
A study to test a combo treatment using electric field stimulation and nitric oxide to boost healing in diabetic foot ulcers.
-
Wound fluid test to predict healing in diabetic foot ulcers
This project looks for chemical signals in the fluid from diabetic foot ulcers that could tell adults with diabetes whether a wound will heal with standard care or need a different treatment.
-
MTX-001 for healing diabetic foot ulcers in people with diabetes
A first–in–class biologic therapy called MTX-001 is being tested to help heal diabetic foot ulcers and reduce infection risk in adults with diabetes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.