Understanding and Improving Healing for Diabetic Wounds
Regulatory Mechanisms Addressing Diabetic Vasculopathy
This work explores new ways to help chronic skin wounds heal better for people living with diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11115766 on NIH RePORTER |
What this research studies
Many people with diabetes experience chronic skin wounds that are difficult to heal, often due to poor blood flow. Current treatments, like those using VEGF, haven't always worked as well as hoped. This project aims to understand why these treatments fall short and to develop new approaches that combine different healing molecules. By looking at how certain fats in the body influence healing, we hope to create a more effective treatment that can significantly improve wound closure.
Who could benefit from this research
Good fit: This research is relevant for adults aged 21 and older who experience chronic skin wounds related to adult-onset diabetes.
Not a fit: Patients without chronic diabetic wounds or those not meeting the age criteria would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for chronic diabetic wounds, improving healing rates and reducing complications.
How similar studies have performed: While VEGF therapy alone has shown limited success, combining it with other molecules is a promising, yet still developing, approach.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Singh, Kanhaiya — University of Pittsburgh at Pittsburgh
- Study coordinator: Singh, Kanhaiya
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.