Understanding and disrupting the processes that allow cancer to spread to the brain.
Deconvolution and interruption of the cancer-neuro-immune axis facilitating brain metastases
This study is looking into how cancer spreads to the brain, which can happen to many cancer patients, and aims to find better ways to treat this issue by exploring how cancer interacts with the brain and immune system, so that patients can eventually benefit from new treatment options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10925234 on NIH RePORTER |
What this research studies
This research focuses on the mechanisms that lead to brain metastases in cancer patients, which affect up to 40% of those diagnosed with cancer. By collaborating with experts in brain and cancer research, the team aims to improve understanding and treatment options for this challenging condition. The project involves innovative approaches to study the cancer-neuro-immune interactions that facilitate tumor growth in the brain, utilizing human brain specimens and advanced technologies. Patients may benefit from new therapeutic strategies developed through this research.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients who have developed brain metastases.
Not a fit: Patients with primary brain tumors or those without any history of cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve survival and quality of life for patients with brain metastases.
How similar studies have performed: Previous research has shown promise in understanding cancer metastasis, but this specific approach targeting the cancer-neuro-immune axis is relatively novel.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Hayden Gephart, Melanie — Stanford University
- Study coordinator: Hayden Gephart, Melanie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.