Understanding and developing treatments for Spinocerebellar Ataxias
Circuit Modulation in Spinocerebellar Ataxias: Mechanisms and Impact
['FUNDING_CAREER'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11051670
This study is looking at Spinocerebellar Ataxias (SCAs) to better understand how they affect coordination and balance, with the hope of finding new treatments that could help improve the lives of people living with these conditions.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-11051670 on ClinicalTrials.gov |
What this research studies
This research focuses on Spinocerebellar Ataxias (SCAs), which are hereditary neurodegenerative disorders that affect coordination, speech, and balance. The principal investigator, Dr. Srinivasan, is developing new therapeutic approaches by studying the underlying mechanisms of these conditions using advanced techniques such as genetic manipulation and electrophysiology in animal models. The project aims to enhance understanding of SCAs and to identify potential treatments that could improve patient outcomes. Patients may benefit from the development of novel therapies that target the specific pathways involved in these disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Spinocerebellar Ataxias or those with a family history of these hereditary conditions.
Not a fit: Patients with non-hereditary forms of ataxia or other unrelated neurological disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve coordination and balance for patients with Spinocerebellar Ataxias.
How similar studies have performed: Previous research has shown promise in developing therapies for neurodegenerative disorders using similar approaches, indicating potential for success in this area.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SRINIVASAN, SHARAN RAM — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: SRINIVASAN, SHARAN RAM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Animal Disease Models