Understanding and coordinating care for liver cirrhosis
Official title: Liver Cirrhosis Network: Scientific and Data Coordination Center
Funded at Northwestern University at Chicago · NIH-10909264 · Data updated 2026-11-12
This study is all about finding better ways to help people with liver cirrhosis by looking at different treatments and lifestyle changes, so we can improve their health and care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | August 28, 2021 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $2,192,940 |
| NIH project number | 5U24DK130164-04 |
| Project ID | NIH-10909264 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with liver cirrhosis or those at risk of developing the condition.
✕Less likely to help
Patients with liver conditions unrelated to cirrhosis or those who are not eligible for any of the proposed treatment options may not benefit from this research.
What this research studies
This research focuses on improving the management of liver cirrhosis, a serious condition that can lead to severe health complications. It aims to gather and analyze data to better understand the disease and its treatment options, including lifestyle changes and medications like statins and beta-blockers. By coordinating scientific efforts and clinical trials, the project seeks to enhance patient care and outcomes for those suffering from cirrhosis. The research will involve collaboration among various healthcare providers and institutions to ensure comprehensive data collection and analysis.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and better health outcomes for patients with liver cirrhosis.
How similar studies have gone: Previous research has shown promising results with similar treatment approaches, particularly with statins, although this specific coordination effort is novel.
Where this research is happening
-
Northwestern University at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Ciolino, Jody D. — Northwestern University at Chicago
- Study coordinator: Ciolino, Jody D.
Related research
Other NIH-funded projects on the same topics.
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Liver Cirrhosis Network: Centers for Clinical Research
A multicenter study in people with cirrhosis from different causes (including HIV, NASH, and alcohol-related liver disease) to collect data and samples and test new ways to predict and monitor disease progression.
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Liver Cirrhosis Network: Mayo Clinic's Clinical Research Center
A Mayo Clinic-led project will follow and help people with compensated cirrhosis, using data, imaging, and a big AI tool to predict when complications may happen and test whether a statin can improve outcomes.
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Liver Cirrhosis Network: Longitudinal and Clinical Trial Studies
A network-wide NIH study focused on understanding cirrhosis better to prevent complications and improve care for people with advanced liver disease.
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Liver Cirrhosis Network: Coordinating Data for Better Care
A national effort is coordinating data to improve care for people with advanced liver disease and its complications.
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Liver Cirrhosis Network coordinating cirrhosis studies and a rosuvastatin trial
This project follows people with liver cirrhosis over time and tests whether the cholesterol medicine rosuvastatin helps people with cirrhosis.
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First-in-class treatment for liver cirrhosis with portal hypertension
A new therapy called XFB19 aims to reduce liver inflammation and scarring in people with advanced liver disease and portal hypertension.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.