Understanding and Addressing Physical Frailty in People with HIV

HIV and musculoskeletal frailty: implications for care, policy and research

['FUNDING_R01'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-11090386

This project aims to help doctors better understand and manage physical frailty in people living with HIV.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorBRIGHAM AND WOMEN'S HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-11090386 on ClinicalTrials.gov

What this research studies

Many people living with HIV are now living longer, but they often experience physical frailty earlier than expected. This frailty can lead to falls, fractures, and loss of independence. Currently, routine screening and management for physical frailty are not standard in HIV care. This work seeks to provide important information to healthcare providers and decision-makers about how to diagnose, prevent, and reduce physical frailty in people with HIV.

Who could benefit from this research

Good fit: This work is relevant for individuals living with HIV who are experiencing or are at risk of developing physical frailty.

Not a fit: Patients who do not have HIV or are not experiencing physical frailty may not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to better guidelines and practices for identifying and treating physical frailty, improving the quality of life for people with HIV.

How similar studies have performed: Evidence suggests that early stages of physical frailty can be reversed with timely diagnosis and effective interventions, though this has not yet been widely translated into routine HIV care.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus, Cardiovascular Diseases

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.