Understanding and addressing lung cancer risks in Native Hawaiians.

Project 2: Mitigating Lung Cancer Disparities in Native Hawaiians: A Population-Based Approach to Evaluate Prevention Barriers and Lung Tumor Biology

NIH-funded research University of Hawaii at Manoa · NIH-10931598

This study is looking at why Native Hawaiians have a higher risk of lung cancer and worse survival rates compared to others, and it aims to find ways to improve early detection and prevention, especially through low-dose CT scans, by understanding the unique challenges this community faces.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Hawaii at Manoa NIH-funded
Lab location1 site (Honolulu, United States)
Project IDNIH-10931598 on NIH RePORTER

What this research studies

This research investigates the higher risk and poorer survival rates of lung cancer among Native Hawaiians compared to other populations. It focuses on identifying barriers to lung cancer prevention and screening, particularly the use of low-dose Computed Tomography (LDCT) for early detection. The study will analyze genetic, epigenetic, and behavioral factors that contribute to these disparities, aiming to improve lung cancer outcomes in this community. By engaging with the local population, the research seeks to develop tailored interventions that address specific needs and challenges.

Who could benefit from this research

Good fit: Ideal candidates for this research include Native Hawaiians aged 50 to 80 years with a history of smoking or those who have quit within the past 15 years.

Not a fit: Patients who do not identify as Native Hawaiians or do not meet the age and smoking history criteria may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved lung cancer prevention and early detection strategies for Native Hawaiians, ultimately enhancing survival rates.

How similar studies have performed: Previous research has successfully identified disparities in lung cancer risk among different populations, suggesting that targeted approaches can lead to meaningful improvements in health outcomes.

Where this research is happening

Honolulu, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.