Understanding and addressing colorectal cancer disparities in African American and Alaska Native populations
Official title: Translational Research Program in Colorectal Cancer Disparities
Funded at Fred Hutchinson Cancer Center · NIH-10935386 · Data updated 2026-11-12
This study is looking into why African American and Alaska Native people have different outcomes when it comes to colorectal cancer, and it aims to find new ways to improve screening and treatment specifically for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $2,575,782 |
| NIH project number | 1P50CA285275-01A1 |
| Project ID | NIH-10935386 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include African American and Alaska Native individuals who are at risk for or diagnosed with colorectal cancer.
✕Less likely to help
Patients outside of the African American and Alaska Native populations may not receive direct benefits from this research.
What this research studies
This research investigates the significant disparities in colorectal cancer (CRC) outcomes among African American and Alaska Native individuals. It aims to uncover the underlying biological and genetic factors that contribute to these disparities, beyond just access to healthcare. By utilizing advanced biotechnology and molecular genetics, the research team will develop improved screening methods and treatment strategies tailored to these populations. The project focuses on creating risk prediction models and identifying novel biological markers that can enhance early detection and treatment responses.
Why it matters
Potential benefit: If successful, this research could lead to more effective prevention and treatment strategies for colorectal cancer in underserved populations.
How similar studies have gone: Previous research has shown success in addressing health disparities through targeted interventions, making this approach promising yet still innovative.
Where this research is happening
-
Fred Hutchinson Cancer Center
Seattle, United States Active
Researchers
- Principal investigator: Peters, Ulrike — Fred Hutchinson Cancer Center
- Study coordinator: Peters, Ulrike
Related research
Other NIH-funded projects on the same topics.
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Improving colorectal cancer screening and follow-up care.
This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.
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A large, multi-center study follows people newly diagnosed with colorectal cancer to find biomarkers and patterns that predict outcomes and guide future care.
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A fast, affordable blood test using DNA markers to help identify people at higher risk of colorectal cancer in low- and middle-income countries.
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Rewiring Colorectal Cancer to Harness Therapeutic Hyperactivation
A Yale team is exploring brain-storming new ways to treat colorectal cancer by safely boosting certain cancer signaling pathways to kill cancer cells and by reshaping cancer cell states to improve responses to existing therapies.
-
Comparative modeling to guide colorectal cancer screening and care
A researcher team will use computer models to study how access to care, risk, and new screening options affect colorectal cancer outcomes and costs for adults in the US.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.