Understanding Alzheimer's genetics in African and Hispanic communities
Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)
This project will collect genetic and health information from African, African American, African Caribbean, and Hispanic people with and without Alzheimer's to help improve knowledge about Alzheimer's risk in these groups.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11380116 on NIH RePORTER |
What this research studies
If you join, researchers will ask about your health and memory, collect a DNA sample (usually saliva or blood), and record basic medical and demographic information. The team is focusing on people of African and Hispanic ancestry and plans community-sensitive recruitment to address mistrust and improve participation. Samples and data will be genotyped and combined into a large resource to find genetic risk factors that may differ by ancestry. The resource aims to make future research and potential treatments more relevant to these underserved communities.
Who could benefit from this research
Good fit: Adults of African, African American, African Caribbean, or Hispanic/Latino ancestry, with or without Alzheimer's disease or related dementia, who are willing to provide health information and a DNA sample are ideal candidates.
Not a fit: People who do not identify as African or Hispanic ancestry, or those unwilling to provide DNA or health information, may not be included and are less likely to benefit directly from this resource.
Why it matters
Potential benefit: If successful, this work could reveal genetic risks specific to African and Hispanic groups and help guide fairer diagnosis, risk prediction, and future therapies.
How similar studies have performed: Prior genetic studies in European and some African American groups have identified risk genes like APOE and ABCA7, but work in African and Hispanic populations has been limited and underpowered, so this larger effort builds on promising but incomplete findings.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Pericak-Vance, Margaret a. — University of Miami School of Medicine
- Study coordinator: Pericak-Vance, Margaret a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.