Understanding Alzheimer's Disease with Advanced Brain Scans
High-dimensional Modeling of PET for radiomic Biomarker Discovery
This project aims to create better ways to analyze brain scans from people with Alzheimer's disease to find important markers of the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brown University NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project ID | NIH-11088892 on NIH RePORTER |
What this research studies
We are developing new statistical tools to look closely at brain imaging data, specifically PET scans, from individuals living with Alzheimer's disease. These tools will help us find unique patterns and changes in the brain over time, which we call biomarkers. By combining information from PET scans with MRI scans, we hope to get a more complete picture of how Alzheimer's progresses. This work will help researchers better understand the disease and identify differences in how it affects various groups of patients.
Who could benefit from this research
Good fit: This research focuses on data from patients previously diagnosed with early-onset and late-onset Alzheimer's disease.
Not a fit: Patients without Alzheimer's disease would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to earlier and more accurate detection of Alzheimer's disease and help guide the development of new treatments.
How similar studies have performed: While the specific statistical methods are novel, similar approaches using imaging data to identify disease biomarkers have shown promise in other neurological conditions.
Where this research is happening
Providence, United States
- Brown University — Providence, United States (Active)
Researchers
- Principal investigator: Eloyan, Ani — Brown University
- Study coordinator: Eloyan, Ani
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.