Understanding Alzheimer's disease through brain tissue analysis
Neuropathology Core
['FUNDING_P30'] · DUKE UNIVERSITY · NIH-10889957
This study at Duke University is all about helping researchers understand Alzheimer's disease better by looking at brain and other tissue samples from people who were monitored before they passed away, so they can improve how we diagnose and treat this condition.
Quick facts
| Phase | ['FUNDING_P30'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DUKE UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-10889957 on ClinicalTrials.gov |
What this research studies
This research focuses on the Neuropathology Core at Duke University, which plays a vital role in diagnosing Alzheimer's disease by analyzing brain and other tissues from individuals who have been closely monitored before their passing. The Core collects and stores high-quality postmortem samples, including blood and cerebrospinal fluid, to support innovative studies on Alzheimer's and related dementias. By providing essential diagnostic support and training to researchers, the Core aims to enhance the understanding of the biological factors contributing to Alzheimer's disease and improve diagnostic methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias who have agreed to donate their postmortem tissues for research purposes.
Not a fit: Patients who are not diagnosed with Alzheimer's disease or related dementias may not receive any direct benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and better understanding of Alzheimer's disease, ultimately improving patient care and treatment options.
How similar studies have performed: Previous research has shown success in utilizing postmortem tissue analysis to advance understanding of Alzheimer's disease, making this approach both established and promising.
Where this research is happening
DURHAM, UNITED STATES
- DUKE UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, SHIH-HSIU JERRY — DUKE UNIVERSITY
- Study coordinator: WANG, SHIH-HSIU JERRY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease