Understanding Alzheimer's Disease in Patients with Other Health Conditions
Official title: Project 2
Funded at Cleveland Clinic Foundation · NIH-11169751 · Data updated 2026-11-12
This project aims to better understand how Alzheimer's disease affects people who also have other health issues like high blood pressure or diabetes, focusing on what matters most to patients and their caregivers.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Foundation NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | September 1, 2015 |
| Project end | June 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $69,701 |
| NIH project number | 5P20GM109025-10 |
| Project ID | NIH-11169751 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this type of work would be individuals living with Alzheimer's disease who also have other health conditions such as high blood pressure or diabetes, along with their caregivers.
✕Less likely to help
Patients without Alzheimer's disease or related neurodegenerative disorders, or those without the specific comorbidities being focused on, may not directly benefit from this particular outcome measurement project.
What this research studies
We want to find better ways to measure how Alzheimer's disease impacts daily life, especially for individuals who also manage other health problems. Currently, many studies rely on doctors' or caregivers' observations, but we believe it's important to hear directly from patients about their experiences. By using patient-centered outcomes, we hope to make research more relevant and help patients stay involved in their care. This approach could lead to treatments that truly improve quality of life.
Why it matters
Potential benefit: If successful, this work could lead to more accurate ways of measuring Alzheimer's disease progression and treatment effectiveness from the patient's perspective, potentially improving patient engagement and quality of life.
How similar studies have gone: While clinical outcome measures are common, research in neurodegenerative disorders has been slow to prioritize patient-reported outcome measures, making this approach less explored in this specific context.
Where this research is happening
-
Cleveland Clinic Foundation
Cleveland, United States Active
Researchers
- Principal investigator: John, Samantha E. — Cleveland Clinic Foundation
- Study coordinator: John, Samantha E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.